Mechanisms for dissociating proteoglycan aggregates.

The Neural Mechanisms of Relational Reasoning: Dissociating Representational Types

The ability to reason about information is an essential human capability. It is less understood from the perspective of neurocognitive processes which can serve to constrain cognitive theories by implications from neuroscientific data. Despite some progress in the last decades, some disagreement about the experimental results and the cognitive processes of reasoning with abstract relations vers...

Dissociating Neural Mechanisms of Temporal Sequencing and Processing Phonemes

Using fMRI, we sought to determine whether the posterior, superior portion of Broca's area performs operations on phoneme segments specifically or implements processes general to sequencing discrete units. Twelve healthy volunteers performed two sequence manipulation tasks and one matching task, using strings of syllables and hummed notes. The posterior portion of Broca's area responded specifi...

Dissociating Neural Mechanisms of Temporal Sequencing and Processing Phonemes

The link protein in proteoglycan aggregates from the Swarm rat chondrosarcoma.

Aggregated proteoglycans (70% aggregated), isolated from the Swarm rat chondrosarcoma by extraction with 4 M guanidinium chloride in the presence of protease inhibitors and purified by centrifugation in an associative cesium chloride gradient, were separated into the component parts by centrifugation in a dissociative cesium chloride gradient. The gradient was cut into five equal fractions. The...

Isolation and preliminary characterization of proteoglycan aggregates from cultured dermal fibroblasts.

A1 proteoglycan fractions were prepared by isopycnic cesium chloride density gradient centrifugation from early passage cultured fibroblasts derived from the skin of human infants. In five different fibroblast strains, A1 preparations from the medium and the cells, respectively, contained 36-63% and 59-79% of the sulfated proteoglycans applied to the gradients. A subpopulation of A1 proteoglyca...